Papaya (Carica papaya L.) as an Effective Adjuvant to Cancer Therapy
Papaya (Carica papaya L.) as an Effective Adjuvant to Cancer Therapy
Papaya (Carica papaya L.) as an Effective Adjuvant to Cancer Therapy
therapy-salar-hafez-ghoran-fatemeh-taktaz-seyed-abdulmajid-ayatollahi
Cancer is one of the deadliest diseases in the world. As per a report of the World Health Organization, it causes more deaths than cardiovascular disease. Since prehistoric times, medicinal plants have been recognized for their potential and effectiveness in treating many diseases and disorders. In this respect, screening indigenous plants for the presence of anticancer components deserves more effort. Recent studies show that papaya (Carica papaya L.; Caricaceae family) and its related secondary (or specialized) metabolites can be used to treat many different types of cancer. Despite papaya’s main use as food, various parts of its tree, such as roots, barks, fruits, latex, and seeds, have been conventionally used for health promotion and to improve disease conditions. The plant contains several phenolic compounds including phenylpropanoid derivatives, flavonoids, glucosinolates, and carotenoids, which are significantly in charge of biological properties to treat various human and veterinary diseases. This chapter will provide a summary of applying different parts of papaya against cancer, and the cellular and molecular targets are also covered. The information presented could be useful to develop either a novel formulation of Carica papaya extract or a kind of plant preparation for cancer therapy.
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